P41: Therapeutic Effect of Transplanting Neural Stem Cells Derived Bone Marrow Stromal Cells Using Bioactive Substance TNT, for Enhance Recovery from Spinal Cord Injury

نویسندگان

Barati , Parastoo Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.

Darvishi , Marzieh Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran.

Moradi , Alireza Department of Physiology, Islamic Azad University of Qom, Qom, Iran.

Tiraihi , Taghi Department of Anatomy, Tarbiat Modares University, Tehran, Iran.

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p41: therapeutic effect of transplanting neural stem cells derived bone marrow stromal cells using bioactive substance tnt, for enhance recovery from spinal cord injury

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Improvement of Spinal Cord Injury in Rat Model via Transplantation of Neural Stem Cells Derived From Bone Marrow

Abstract Background & Aims: Cell therapy is among the novel therapeutic methods effective in the treatment of spinal cord injuries. The aim of the present study was using neural stem cells (NSCs) in treating contusion spinal cord injury in rat model. Methods: Bone marrow stromal cells (BMSCs) were isolated from adult rats...

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in the last few years, a lot of preclinical studies showed the therapeutic potential of stem cells in spinal cord injury (sci). neural stem cells (nscs) can be differentiated into all cell types of spinal cord. nscs are cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair of injury in central nervous system. here in, we describe the ef...

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Transplanting P75-Suppressed Bone Marrow Stromal Cells Promotes Functional Behavior in a Rat Model of Spinal Cord Injury

Background: Bone marrow stromal cells (BMSC) have been successfully employed for movement deficit recovery in spinal cord injury (SCI) rat models. One of the unsettled problems in cell transplantation is the relative high proportion of cell death, specifically after neural differentiation. According to our previous studies, p75 receptor, known as the death receptor, is only expressed in BMSC in...

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